The 86-year-old Playboy magazine founder exchanged vows with his "runaway bride," Crystal Harris, at a private Playboy Mansion ceremony on New Year's Eve.
Ms Harris, a 26-year-old "Playmate of the Month" in 2009, broke off a previous engagement to Mr Hefner just before they were to be married in 2011.
Playboy said on Tuesday that the couple celebrated at a New Year's Eve party at the mansion with guests that included comic Jon Lovitz, Gene Simmons of KISS and baseball star Evan Longoria.
The bride wore a strapless gown in soft pink, Mr Hefner a black tux. Mr Hefner's been married twice before but lived the single life between 1959 and 1989.