The three-hour show - hosted by hip-hop artist Ludacris and former High School Musical star Vanessa Hudgins - included performances by Miley Cyrus, the Chainsmokers, Nicki Minaj and Imagine Dragons.
Beyonce and Twenty One Pilots each took five awards, although they were absent from the ceremony. The Chainsmokers earned four, including top collaboration and top hot 100 song for Closer with Halsey.
Blake Shelton took home the award for top country artist, and top country song went to Florida Georgia Line.
Justin Timberlake's Can't Stop the Feeling won top selling song and top radio song.
The Icon Award for achievement in music went to Cher, 71, who gave a heartfelt speech after performing two of her biggest hits - Believe and If I Could Turn Back Time.
"I want to thank my mom because when I was really young, my mom said 'You're not going to be the smartest. You're not going to be the prettiest. You're not going to be the most talented, but you're going to be special,'" Cher said.
Canadian singer Celine Dion delivered an emotional performance of her award-winning song My Heart Will Go On from the soundtrack of the movie Titanic to mark 20 years since its release.
Celine Dion, who was Billboard's Icon last year, lost her husband and former manager Rene Angelil to cancer in 2016.
Here's the complete list of winners:
Top Artist: Drake
Top New Artist: Zayn
Billboard Chart Achievement Award Presented by Xfinity: Twenty One Pilots
Top Male Artist: Drake
Top Female Artist: Beyonce
Top Duo/Group: Twenty One Pilots
Top Billboard 200 Artist: Drake
Top Hot 100 Artist: Drake
Top Song Sales Artist: Drake
Top Radio Songs Artist: Twenty One Pilots
Top Streaming Songs Artist: Drake
Top Social Artist: BTS
Top Touring Artist: Beyonce
Top R&B Artist: Beyonce
Top R&B Tour: Beyonce
Top Rap Artist: Drake
Top Rap Tour: Drake
Top Country Artist: Blake Shelton
Top Country Tour: Kenny Chesney
Top Rock Artist: Twenty One Pilots
Top Rock Tour: Coldplay
Top Latin Artist: Juan Gabriel
Top Dance/Electronic Artist: The Chainsmokers
Top Christian Artist: Lauren Daigle
Top Gospel Artist: Kirk Franklin
Top Billboard 200 Album: Drake, Views
Top Soundtrack/Cast Album: Hamilton: An American Musical
Top R&B Album: Beyonce, Lemonade
Top Rap Album: Drake, Views
Top Country Album: Chris Stapleton, Traveller
Top Rock Album: Metallica, Hardwired...To Self Destruct
Top Latin Album: Juan Gabriel, Los Duo 2
Top Dance/Electronic Album: Lindsey Stirling, Brave Enough
Top Christian Album: Lauren Daigle, How Can It Be
Top Gospel Album: Tamela Mann, One Way
Top Hot 100 Song: The Chainsmokers Featuring Halsey, Closer
Top Selling Song: Justin Timberlake, Can't Stop The Feeling!
Top Radio Song: Justin Timberlake, Can't Stop The Feeling!
Top Streaming Song (Audio): Drake Featuring WizKid & Kyla, One Dance
Top Streaming Song (Video): Desiigner, Panda
Top Collaboration: The Chainsmokers Featuring Halsey, Closer
Top R&B Song: Drake Featuring WizKid & Kyla, One Dance
Top R&B Collaboration: Drake Featuring WizKid & Kyla, One Dance
Top Rap Song: Desiigner, Panda
Top Rap Collaboration: Rae Sremmurd Featuring Gucci Mane, Black Beatles
Top Country Song: Florida Georgia Line, H.O.L.Y.
Top Country Collaboration: Kenny Chesney Featuring Pink, Setting The World On Fire
Top Rock Song: Twenty One Pilots, Heathens
Top Latin Song: Nicky Jam, Hasta El Amanecer
Top Dance/Electronic Song: The Chainsmokers Featuring Halsey, Closer
Top Christian Song: Hillary Scott & The Family, Thy Will
Top Gospel Song: Travis Greene, Made A Way
(Except for the headline, this story has not been edited by NDTV staff and is published from a syndicated feed.)