The filmmaker, who died on March 1, 1994, directed hit films like Amar Akbar Anthony, Naseeb and Parvarish with Big B in the 1970s and the 1980s.
Big B's tweet on Wednesday was accompanied by images featuring them together:
T 2161 - Manmohan Desai .. left us today years ago, years i do not wish to remember .. I miss you Man ji !! pic.twitter.com/FuZoRVJYKV— Amitabh Bachchan (@SrBachchan) March 1, 2016
Big B also suffered a near-fatal accident while shooting an action scene for Mr Desai's Coolie in 1982.
He shared on his official blog that how "memories keep going".
"Remembrance is an exercise by itself, painful and frustrating. For when you need that word or name, it just does not come. It hangs incognito at the tip of your cranial cells but refuses to give the joy of its exactitude immediately. You or rather one searches equivalent expressions to come to the right word, and so blessed for this Google thingy. It's the boon of the generation. But they say it's fast going out of fashion," he wrote.
He shared about shooting in Kamalistan Studio as well. "And so to work at Kamalistan Studios... an expanse of studio land belonging to that great legend, Kamal Amrohi. The husband to Meena Kumari, the maker of so many iconic films, in particular Pakeeza," the 73-year-old wrote.
"The blue and the white cross marks are the modern generation cinema technology. When it is all set and done an entire chemical laboratory shall be placed around me through which I walk... and not just me, but two more of me. I mean the same me but three of me," he expressed sharing photographs of himself in "formals, rural, aggressive and finally laid-back" looks.
He also posted a photograph of himself in which he is seen holding an award for his performance in Piku.
"And my Zee Awards Best actor trophy which I could not go to receive because of my condition. Receiving it now on camera," wrote Big B, who is recovering from a mild neck ailment.
He also shared an update about his look in Shoojit Sircar's next. (Also Read: Amitabh Bachchan Experienced 'Withdrawal Symptoms' After Te3n Wrap)
"The beard and the hair grows for the next for Shoojit Sircar. Random and without care. Contemplative, lost in mood, bipolar in form," he wrote.