The gunman, identified by officials as Afghan-origin Omar Mateen, 29, was killed by a SWAT team after he took hostages at Pulse, the popular gay nightclub.
Here's what the Bollywood celebrities had to say:
Sad,Orlando. Condolences! Hope this does not become political mileage for any. Again one rotten apple story.......? Kabhi socho sahi hai (@chintskap) June 12, 2016
Heart goes out to all families devastated by the Orlando shooting.. Your grief is unimaginable and we share it with you. In solidarity..? Farhan Akhtar (@FarOutAkhtar) June 13, 2016
Heartbreaking to hear about the #OrlandoNightclubShooting!!! Can just imagine what the families and people are going through. Shocked!!? Alia Bhatt (@aliaa08) June 13, 2016
Heartbreaking to hear about #OrlandoNightclubShooting , prayers to the all the family's who have lost their loved ones .? Tamannaah Bhatia (@tamannaahspeaks) June 13, 2016
What happened in Orlando towards the gay and lesbian community is absolutely horrible. My love and support goes out to everyone!? Sunny Leone (@SunnyLeone) June 13, 2016
May the victims of Orlando shooting rest in peace. May God give their kith & kin strength and courage. May this not usher a pro Trump stand.? Ayushmann Khurrana (@ayushmannk) June 13, 2016
Love and prayers for the people of Orlando.God give strength to all the victims,families and friends.Let's all stand tall against terrorism.? arjun rampal (@rampalarjun) June 13, 2016
Appalling! Awful! Terrible! Prayers to the #OrlandoShooting victims & strength to their families!? Pulkit Samrat (@PulkitSamrat) June 13, 2016
#OrlandoNightclubShooting Prayers to the family's of the victims. The US needs a serious review of its gun control policy.? kunal kohli (@kunalkohli) June 13, 2016
Actress Bipasha Basu wrote on Twitter: "Prayers for peace #OrlandoShooting."
Sonam Kapoor Instagrammed: