Irrfan Khan moved to Mumbai to pursue his dream of becoming an actor. He featured in numerable television serials like Chanakya, Bharat Ek Khoj, Sara Jahan Hamara, Banegi Apni Baat, Chandrakanta, Shrikant. He was also part of Sparsh, which aired on Star Plus.
Irrfan Khan was the main villain in a series called Darr (which aired on Star Plus), where he played the role of a psycho serial killer opposite Kay Kay Menon. He also featured as Lenin in a teleplay named Laal Ghaas Par Neele Ghode.