The year 1999 was a good one for Twinkle. She starred opposite Akshay Kumar, now her husband, in International Khiladi, the sixth installment the Khiladi series. Twinkle played the role of a news reporter in the action-thriller, which was a hit at the box office. She was also seen with Akshay in Zulmi the same year, but the film didn't do well at the box office. In 1999, she starred in Telugu film Seenu.