"If your show doesn't have a dragon or a white Bronco in it, go home right now." - Emmys host Jimmy Kimmel, joking in his opening monologue about the dominance of Game of Thrones and The People vs OJ Simpson: American Crime Story, which became reality as the night proceeded
The blood-spattered, sex-filled saga about noble families vying for control of the Iron Throne took home the most coveted prize of the night, the best drama Emmy - along with statuettes for writing and directing
Rami Malek of Mr. Robot and Tatiana Maslany of Orphan Black won for Best Actor and Best actress in the Drama Series category
Before the Emmy Awards on Sunday night, take a look at the major match-ups and make some predictions. Here's a list of probable winner, who deserves to win and the dark horse in primary categories
Game of Thrones picked up nine statuettes at last weekend's Creative Arts Emmys, which reward artistic and technical achievement, giving it a total haul over the years of 35 - more than any other drama series
For the first time, the awards are being handed out over two nights. On night one, Game of Thrones took home highest number of wins, earning in categories like casting, visual effects, stunt coordination and production design
Jon Snow was surprisingly killed off in season five angering fans. He, however, was brought back to life in the beginning of sixth season.
"If I could get them to do more, I would take 10 seasons, but we want to take their lead with what they can do and what the best version of the show is," HBO's programming chief Casey Bloys said.
"Now that winter has arrived on Game of Thrones, executive producers David Benioff and D B Weiss felt that the storylines of the next season would be better served by starting production a little later than usual, when the weather is changing," Casey Bloys, President, HBO Programming, said in a statement
Game of Thrones, which raked in a record-breaking 12 awards last year, faces competition from House of Cards, Better Call Saul, Mr. Robot, Downton Abbey, The Americans and Homeland
HBO's fantasy epic about noble families vying for control of the Iron Throne is expected to net a raft of nods after raking in a record-breaking 12 awards last year, including Best Drama Series
The Emmy Awards, the biggest honors in television, will be handed out at a star-studded ceremony in Los Angeles that could see some major surprises - and maybe even a history-making win for black women. Will blood-splattered fantasy epic Game of Thrones finally take home top television honors?